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Breakthrough in Treating 75% of Cancers

Updated: Oct 13, 2023

What if cancer cells are healthy cells that accidentally turned on the program that brings them back to being naïve-state stem cells?


The 2012 Nobel Prize in Physiology for Medicine was awarded jointly to Sir John B. Gurdon and Shinya Yamanaka "for the discovery that mature cells can be reprogrammed to become pluripotent stem cells."


Dr Cynthia Bamdad, the Founder and CEO of Minerva Biotechnologies, theorized and discovered that stem cells grow exactly like cancer cells.


Discovery of the pluripotency “on-off” switch brings the elusive cure for cancer ever closer.

Paradox: If stem cells and cancer cells grow by the same growth factor and growth factor receptor, then how do stem cells turn off self-replication but cancer cells self-replicate forever?


Discovery: Dr. Bamdad theorized then found a primitive growth factor that should be turned off at Day 10 of a

developing embryo but is aberrantly turned on again in cancers. This primitive growth factor is heavily expressed in 75%+ of solid tumor cancers and is the basis for Minerva’s very exciting cancer therapeutics technology. Her discovery of the pluripotency “on-off” switch brings the elusive cure for cancer ever closer.



Impressive Results. Minerva is in FDA approved First-in-Human trials for advanced metastatic breast cancers. Trial participants have failed up to 17 previous lines of treatment and have on average three months life expectancy. Minerva has delivered very substantial extensions of life to more than 60% of trial participants and has totally reversed cancer metastasis in advanced animal models.

Dr. Cynthia Bamdad holds a B.S. in Physics and a Ph.D. in Biophysics from Harvard, where she was a Howard Hughes fellow. While a Ph.D. student, Dr. Bamdad invented the first electronic DNA chip and the first universal protein chip. After continued success in biotechnology field Bamdad founded Minerva Biotechnologies to focus on stopping solid tumor cancers based on her discovery that the growth of embryonic stem cells and cancer cells is mediated by the same growth factor and growth factor receptor. By studying stem cells and cancer cells in parallel, she discovered how stem cells limit self-replication and how cancer cells override the natural shut-off switch to self-replicate forever. Dr. Bamdad is the sole or co-inventor of over 100 patent applications in the US and foreign jurisdictions for novel technologies, stem cell technologies, cancer therapeutics and diagnostics.


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